New Releases by Siddhartha Mukherjee

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee's revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer's exploration of what it means to be human. Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves--hearts, blood, brains--are built from these compartments. Hooke christened them "cells". The discovery of cells--and the reframing of the human body as a cellular ecosystem--announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia--all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces you with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjee's own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate--a masterpiece.

The book provides the whole horizon of process engineering and plant design from concept phase through the execution to commissioning of the plant in the real practice. Providing a complete industrial perspective, the book: Covers the guidelines and standards followed in the industry and how engineering documents are generated using these standards Describes Hazardous Area Classification, Relief System Design, Revamp Engineering, Interaction with Other Disciplines, and Pre-commissioning and Commissioning Contains several illustrated practical examples, which clarify the fundamentals to a raw chemical engineer Includes description of a complete chemical project from concept to commissioning Treating the topic from the perspective of an industrial employee with extensive experience in process engineering and plant design, it aims to aid chemical and plant engineers to deal with decision making processes on strategic level, management tasks and leading functions beside the technical know-how.

The book provides the whole horizon of process engineering and plant design from concept phase through the execution to commissioning of the plant in the real practice. Providing a complete industrial perspective, the book: Covers the guidelines and standards followed in the industry and how engineering documents are generated using these standards Describes Hazardous Area Classification, Relief System Design, Revamp Engineering, Interaction with Other Disciplines, and Pre-commissioning and Commissioning Contains several illustrated practical examples, which clarify the fundamentals to a raw chemical engineer Includes description of a complete chemical project from concept to commissioning Treating the topic from the perspective of an industrial employee with extensive experience in process engineering and plant design, it aims to aid chemical and plant engineers to deal with decision making processes on strategic level, management tasks and leading functions beside the technical know-how.

A photo journal of 48 hours spent in the great Mughal cities of Fatehpur Sikri and Agra highlighting the magnificent architecture and an attempt to tell the back stories.

A magnificent, beautifully written biography of cancer - from its first documented appearances thousands of years ago through the epic battles to cure, control and conquer it to a radical new understanding of its essence. In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out `war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary.From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge.Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.

A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

This wide-ranging boxed set of ten TED Books titles covers everything from architecture to business, space travel to love: The Terrorist’s Son, The Mathematics of Love, The Art of Stillness, The Future of Architecture in 100 Buildings, Beyond Measure, Judge This, How We’ll Live on Mars, Why We Work, The Laws of Medicine, and Follow Your Gut. Provocative, intelligent, and forward-thinking, the first ten TED Books is perfect for any curious reader interested in technology, design, and creative thinking. The Terrorist’s Son is the story of the man who planned the 1993 World Trade Center bombing—and the son who chose a different path. The Mathematics of Love is a must-have for anyone who wants to better understand the patterns of their love life. In The Art of Stillness, travel writer Pico Iyer reveals a counterintuitive truth: The more ways we have to connect, the more we seem desperate to unplug. The Future of Architecture in 100 Buildings captures the thoughtful intelligence and the sheer whimsy of the world’s most inspired and future-looking buildings. Beyond Measure reveals how organizations can make huge changes with surprisingly small steps and ultimately transform their company culture. Chip Kidd’s Judge This is a playful look at the importance of first impressions—in design and in life—exposing the often invisible beauty and betrayal in simple design choices ones most of us never even think to notice. In How We’ll Live on Mars award-winning journalist Stephen Petranek makes the case that living on Mars is an essential back-up plan for humanity and will happen far sooner than we imagine. In the groundbreaking Why We Work Barry Schwartz dispels a deeply ingrained myth: The reason we work is primarily to get a paycheck. Pulitzer Prize–winning author Siddhartha Mukherjee reveals an urgent philosophy in The Laws of Medicine on the little-known principles that govern medicine. In Follow Your Gut scientist Rob Knight and journalist Brendan Buhler explain why the microscopic life inside us matters to everyone.

An exciting boxed set collection of must-have TED Books for any science reader—from medical professionals to armchair Internet doctors to sci-fi enthusiasts—an engaging and fresh look at the inner and outer world around us, including Follow Your Gut, How We’ll Live On Mars, and The Laws of Medicine. Allergies, obesity, acne: these are just a few of the conditions that may be caused—and someday cured—by the microscopic life inside us. How does this groundbreaking science influence your health, mood, and more? In Follow Your Gut pioneering scientist Rob Knight pairs with award-winning science journalist Brendan Buhler to explain why these new findings matter to everyone. In How We’ll Live on Mars award-winning journalist Stephen Petranek considers what sounds like science fiction as fact: within twenty years, humans will live on Mars. In fact, we’ll need to. In this sweeping, provocative book that mixes business, science, and human reporting, Petranek makes the case that living on Mars is an essential back-up plan for humanity, and he explains in fascinating detail just how it will happen. The Laws of Medicine is essential, required reading for doctors and patients alike: Pulitzer Prize-winning author of The Emperor of Maladies and one of the world’s premiere cancer researchers, Siddhartha Mukherjee reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all.

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.