Most Popular Books by Robert Pool

We have long recognized technology as a driving force behind much historical and cultural change. The invention of the printing press initiated the Reformation. The development of the compass ushered in the Age of Exploration and the discovery of the New World. The cotton gin created the conditions that led to the Civil War. Now, in Beyond Engineering, science writer Robert Pool turns the question around to examine how society shapes technology. Drawing on such disparate fields as history, economics, risk analysis, management science, sociology, and psychology, Pool illuminates the complex, often fascinating interplay between machines and society, in a book that will revolutionize how we think about technology. We tend to think that reason guides technological development, that engineering expertise alone determines the final form an invention takes. But if you look closely enough at the history of any invention, says Pool, you will find that factors unrelated to engineering seem to have an almost equal impact. In his wide-ranging volume, he traces developments in nuclear energy, automobiles, light bulbs, commercial electricity, and personal computers, to reveal that the ultimate shape of a technology often has as much to do with outside and unforeseen forces. For instance, Pool explores the reasons why steam-powered cars lost out to internal combustion engines. He shows that the Stanley Steamer was in many ways superior to the Model T--it set a land speed record in 1906 of more than 127 miles per hour, it had no transmission (and no transmission headaches), and it was simpler (one Stanley engine had only twenty-two moving parts) and quieter than a gas engine--but the steamers were killed off by factors that had little or nothing to do with their engineering merits, including the Stanley twins'' lack of business acumen and an outbreak of hoof-and-mouth disease. Pool illuminates other aspects of technology as well. He traces how seemingly minor decisions made early along the path of development can have profound consequences further down the road, and perhaps most important, he argues that with the increasing complexity of our technological advances--from nuclear reactors to genetic engineering--the number of things that can go wrong multiplies, making it increasingly difficult to engineer risk out of the equation. Citing such catastrophes as Bhopal, Three Mile Island, the Exxon Valdez, the Challenger, and Chernobyl, he argues that is it time to rethink our approach to technology. The days are gone when machines were solely a product of larger-than-life inventors and hard-working engineers. Increasingly, technology will be a joint effort, with its design shaped not only by engineers and executives but also psychologists, political scientists, management theorists, risk specialists, regulators and courts, and the general public. Whether discussing bovine growth hormone, molten-salt reactors, or baboon-to-human transplants, Beyond Engineering is an engaging look at modern technology and an illuminating account of how technology and the modern world shape each other.

When the leptin gene was discovered in 1994, news articles predicted that there might soon be an easy, pharmaceutical solution to the growing public health crisis of obesity. Yet this scientific breakthrough merely proved once again how difficult the fight against fat really is. Despite the many appetite-suppressants, diet pills, and weight-loss programs available today, approximately 30 percent of Americans are obese. And that number is expanding rapidly. Fat is the engaging story of the scientific quest to understand and control body weight. Covering the entire twentieth century, Robert Pool chronicles the evolving blame-game for fat--from being a result of undisciplined behavior to subconscious conflicts, physiological disease, and environmental excess. Readers in today''s weight-conscious society will be surprised to learn that being overweight was actually encouraged by doctors and popular health magazines up until the 1930s, when the health risks associated with being overweight were publicly recognized. Thus began decades of research and experiments that subsequently explained appetite, metabolism, and the development of fat cells. Pool effectively reanimates the colorful characters, curious experiments, brilliant insights and wrong turns that led to contemporary scientific understanding of America''s epidemic. While he acknowledges the advances in the pharmacological fight against flab, he underscores that the real problem of obesity is not losing the weight but keeping it off. Drugs offer a quick fix, but they aren''t the ultimate answer. American society must remedy the unhealthy daily environments of its cities and towns, and those who have struggled with their weight and have experienced the "yo-yo" cycle of dieting must understand the underlying science of body weight that makes their struggle more than a question of willpower.

“This book is a breakthrough, a lyrical, powerful, science-based narrative that actually shows us how to get better (much better) at the things we care about.”—Seth Godin, author of Linchpin “Anyone who wants to get better at anything should read [Peak]. Rest assured that the book is not mere theory. Ericsson’s research focuses on the real world, and he explains in detail, with examples, how all of us can apply the principles of great performance in our work or in any other part of our lives.”—Fortune Anders Ericsson has made a career studying chess champions, violin virtuosos, star athletes, and memory mavens. Peak distills three decades of myth-shattering research into a powerful learning strategy that is fundamentally different from the way people traditionally think about acquiring new abilities. Whether you want to stand out at work, improve your athletic or musical performance, or help your child achieve academic goals, Ericsson’s revolutionary methods will show you how to improve at almost any skill that matters to you. “The science of excellence can be divided into two eras: before Ericsson and after Ericsson. His groundbreaking work, captured in this brilliantly useful book, provides us with a blueprint for achieving the most important and life-changing work possible: to become a little bit better each day.”—Dan Coyle, author of The Talent Code “Ericsson’s research has revolutionized how we think about human achievement. If everyone would take the lessons of this book to heart, it could truly change the world.”—Joshua Foer, author of Moonwalking with Einstein

The goal of this workshop was to bring together bioinformatics stake holders from government, academe, and industry for a day of presentations and dialogue. Fifteen experts identified and discussed some of the most important issues raised by the current flood of biologic data. Topics explored included the importance of database curation, database integration and interoperability, consistency and standards in terminology, error prevention and correction, data provenance, ontology, the importance of maintaining privacy, data mining, and the need for more computer scientists with specialty training in bioinformatics. Although formal conclusions and recommendations will not come from this particular workshop, many insights may be gleaned about the future of this field, from the context of the discussions and presentations described here.

On August 16, 2000, the Board on Life Sciences held a forum on "Environmental Contamination, Biotechnology, and the Law: The Impact of Emerging Genomic Information." The purpose of the forum was to explore the legal implications of current and developing biotechnology approaches to evaluating potential human health and environmental effects caused by exposure to environmental contaminants and to cleaning up contaminated areas. The forum brought together scientists from academe, government, and industry and members of the legal community, including lawyers and judges, to discuss the interface between the use of those approaches and the legal system.

The etiology of the Wimbum people in the Western Grassfields of Cameroon is described through an examination of the way in which the meanings of key concepts, used to interpret and explain illness and other forms of misfortune, are continually being produced and reproduced in the praxis of everyday communication. During the course of numerous dialogues, witchcraft, a highly ambivalent force, gradually emerges as the prime mover. As destructive cannibals or respectable elders the witches are the ultimate cause of all significant illness, misfortune and death, and as diviners they are also the ultimate judges who apportion moral responsibility. Even the ancestors and the traditional gods turn out to be fronts behind which the witches hide their activities.The study is on three levels: a medical anthropological exploration of explanations of illness and misfortune; a detailed ethnography of traditional African cosmology and witchcraft; and an examination of recent theoretical issues in anthropology such as the nature of ethnographic fieldwork and the possibility of dialogical or postmodern ethnography.

Proponents of agricultural biotechnology believe that genetically modified (GM) crops have the potential to provide great ecological benefits, such as reduced pesticide and land use, as well as agricultural benefits. However, given the rapid emergence of commercial GM crops and the likely increase in their use, many groups have raised concerns about the potential unintended, adverse ecological effects of these crops. Some ecological concerns are enhanced development of pest resistance, crosspollination with wild relatives, and reductions in beneficial insects or birds. Ecological Monitoring of Genetically Modified Crops considers the latest in monitoring methods and technologies and to asks-What are the challenges associated with monitoring for ecological effects of GM crops? Is ongoing ecological monitoring of GM crops a useful and informative activity? If so, how should scientifically rigorous monitoring be carried out in the variety of ecological settings in which GM crops are grown?

In this memoir, Yang-Mills field curvature and current are described as elements of cohomology groups on ambitwistor space, and it is shown that the Yang-Mills current corresponds to the third-order obstruction to extending the corresponding vector bundle. There is also a description of the Yang-Mills field''s action density. In addition, several groups of solutions to various differential equations on Miskowski space are characterized as elements of various cohomology classes over ambitwistor space.

Recognizing the important contributions that genomic analysis can make to agriculture, production and companion animal science, evolutionary biology, and human health with respect to the creation of models for genetic disorders, the National Academies convened a group of individuals to plan a public workshop that would: (1) assess these contributions; (2) identify potential research directions for existing genomics programs; and (3) highlight the opportunities of a coordinated, multi-species genomics effort for the science and policymaking communities. Their efforts culminated in a workshop sponsored by the U.S. Department of Agriculture, Department of Energy, National Science Foundation, and the National Institutes of Health. The workshop was convened on February 19, 2002. The goal of the workshop was to focus on domestic animal genomics and its integration with other genomics and functional genomics projects.

In recent years, the costs of new drug development have skyrocketed. The average cost of developing a new approved drug is now estimated to be $1.3 billion (DiMasi and Grabowski, 2007). At the same time, each year fewer new molecular entities (NMEs) are approved. DiMasi and Grabowski report that only 21.5 percent of the candidate drugs that enter phase I clinical testing actually make it to market. In 2007, just 17 novel drugs and 2 novel biologics were approved. In addition to the slowing rate of drug development and approval, recent years have seen a number of drugs withdrawn from the market for safety reasons. According to the Government Accountability Office (GAO), 10 drugs were withdrawn because of safety concerns between 2000 and March 2006 (GAO, 2006). Finding ways to select successful drug candidates earlier in development could save millions or even billions of dollars, reduce the costs of drugs on the market, and increase the number of new drugs with improved safety profiles that are available to patients. Emerging scientific knowledge and technologies hold the potential to enhance correct decision making for the advancement of candidate drugs. Identification of safety problems is a key reason that new drug development is stalled. Traditional methods for assessing a drug''s safety prior to approval are limited in their ability to detect rare safety problems. Prior to receiving U.S. Food and Drug Administration (FDA) approval, a drug will have been tested in hundreds to thousands of patients. Generally, drugs cannot confidently be linked to safety problems until they have been tested in tens of thousands to hundreds of thousands of people. With current methods, it is unlikely that rare safety problems will be identified prior to approval. Emerging Safety Science: Workshop Summary summarizes the events and presentations of the workshop.

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