Best Selling Books by Jonathan Thomas

Beschreibung The recent rise of bio-succinic acid as an industrial platform chemical has brought the rumen bacterium Basfia succiniciproducens, a natural producer of this organic acid, into the focus of research. This work investigated the potential of B. succiniciproducens for the production of carbon-three chemicals from sugars. Beside the optimization of improved genetic tools, the C3 chemicals alanine, β-alanine and 3-hydroxypropionate (3-HP) were targeted. A new alanine producer, B. succiniciproducens ALA-1, exhibited good performance in the bioprocess. The next step demonstrated the proof-of-concept for β-alanine synthesis using the heterologous expression of aspartate 1 decarboxylase genes from Corynebacterium glutamicum or Vibrio natriegens. The expression of two additional genes enabled the de novo synthesis of up to 100 mg L-1 3-HP from glucose.

Jonathan and Jackie Thomas, founders of the world''s largest Anglophile website Anglotopia.net, set off on their biggest adventure yet as they drove from Land''s End to John o''Groats (aka LeJog), ticking off the top item on their ''Great British Bucket List.'' End to End is a new exploration of Britain from the southernmost tip of Cornwall to the northernmost tip of Scotland. Along the way, they explore stately homes, ruins, castles, the Queen''s private yacht, unique attractions, a bookshop or two, and even a motorway rest stop! This journey takes them over 900 miles through some of the most breathtaking scenery in the UK and to many special places that they''ve never been to before. Along the way, they encounter fascinating characters, experience unexpected challenges, and discover the true spirit of adventure as they get to know Britain in a they''ve never experienced. The journey also serves as a personal pilgrimage for the couple as they reflect on their lives, their business, their passions, and their love for each other. This inspiring and heartwarming tale showcases the beauty of the British countryside and the resilience of the adventurous human spirit. Join Jonathan and Jackie on their unforgettable journey and discover the magic of the UK like never before.

London is a city rich in history and culture, and nowhere is this more evident than in the unique language of its people. In "Londontopia''s Cockney Rhyming Slang Dictionary," readers will be introduced to the fascinating world of Cockney rhyming slang - a form of English that uses playful, often comical phrases to replace common words and expressions. This comprehensive dictionary features hundreds of entries, each accompanied by its meaning and a colorful example of usage. But it''s not just a guide to the language - readers will also find a big section on London''s Cockney history, exploring the origins and evolution of this distinctive dialect. There are also sections on famous Cockneys, relevant TV shows, and so much more! Whether you''re a native Londoner or just a lover of language, "Londontopia''s Cockney Rhyming Slang Dictionary" is an essential resource for anyone interested in the vibrant and unique culture of this great city. Londontopia.net is the world''s largest website dedicated to all things London, with thousands of articles about London''s History, Culture, Travel, and Attractions. Topics Covered: What is a Cockney? Cockney Rhyming Slang History Common Questions about Cockney Slang A History of St Mary-le-Bow Cockney Films and TV Shows Great London Telly: Eastenders Great London Telly: Only Fools and Horses London''s Pearly KIngs and Queens 25 Famous Cockneys and Eastenders 40 London Slang Phrases and Their Histories London Street Slang London Lingo Cockney Slang Dictionary

How Do Dragons Say Hello is a fun and colorful book that helps children practice animal noises by using fantasy creatures to tell a fun rhyme.

An attempt has been made to identify tropical waves with periods less than 20 days in the Indian Ocean by spectrum analysis of radiosonde data for five stations, widely scattered over the Indian Ocean area. The data used is for the period from January to September, 1973, which was further divided into five-month seasons, overlapping in May due to consideration of the monsoonal shift in the mean flow. Three spectral peaks in the 10-17 day, 6-7 day and 4-5 day ranges have been detected. Cross-spectrum analysis reveals a basically in-phase structure in the vertical in the lower troposphere and reversed phase at upper levels. (Modified author abstract).

A dynamic contrast-enhanced (DCE) near-infrared (NIR) method to measure cerebral blood flow (CBF) in the neurocritical care unit (NCU) is described. A primary concern in managing patients with acquired brain injury (ABI) is onset of delayed ischemic injury (DII) caused by complications during the days to weeks following the initial insult, resulting in reduced CBF and impaired oxygen delivery. The development of a safe, portable, and quantitative DCE-NIR method for measuring CBF in NCU patients is addressed by focusing on four main areas: designing a clinically compatible instrument, developing an appropriate analytical framework, creating a relevant ABI animal model, and validating the method against CT perfusion. In Chapter 2, depth-resolved continuous-wave NIR recovered values of CBF in a juvenile pig show strong correlation with CT perfusion CBF during mild ischemia and hyperemia (r=0.84, p

Markov Chain Monte Carlo simulations are used to quantify the relative uncertainties of the transference number estimates to be less than five percent, consistently. The transference number estimates are related to faradaic efficiency loss and capacity fade of working VRFBs operating in the migration-dominated regime. The technique used in this work may be generalized to measure salt transference numbers in novel electrochemical systems and membrane separators to inform their rational design.

Four Na+, K+-ATPase alpha isoforms have been identified and characterized in the rat. In humans, three isoforms have been characterized and evidence has been provided suggesting the existence of a fourth alpha isoform. The goal of this study was to isolate and characterize the fourth human alpha isoform. This was accomplished by cloning the cDNA from human testis libraries and expressing it in HeLa cells. Sequence analysis demonstrates that the deduced amino acid sequence shares high homology with the other three human alpha isoforms and the rat alpha 4 isoform. Using an alpha 4 specific antibody, a protein ~100 kDa was identified through western blotting and it was localized to the flagellum of the sperm by immunohistochemistry. These results confirm the existence of the human alpha 4 Na+, K+-ATPase isoform and its localization to sperm suggest that the human alpha 4 isoform plays a role in the function human sperm.

According to the Labour Force Survey, about 20% (approximately 7.5 million) of the non-student working-age population were not in paid employment in 2002. Of these people about one in five were classified as unemployed, with the remainder labelled as ''inactive.'' Despite this categorisation, however, some groups in the so-called inactive population are as likely to move into employment as those classified as unemployed, so any comprehensive measure of labour availability needs to incorporate information on the characteristics of the non-employed pool as a whole. This paper describes the key trends in the demographic and skill structure of the non-employed population since the mid-1980s and contrasts them with those in employment. It also attempts to draw out the implications of these trends for overall labour availability, building on recent Bank research which models individual transition rates from non-employment into employment.

The global economy is changing: experts are noting slow growth in the advanced economies, greater volatility in international markets, and the emergence of state-owned companies in the competitive marketplace. This forward-looking reference explores the role that state capitalism plays within the political structures of countries throughout the world. The text begins with an introduction to state capitalism, moves into an in-depth examination of several countries and regions, and concludes with a discussion on the future of state capitalism in the next decade. Coauthors Scott B. MacDonald.

Céu do Mapiá is a community of people living in the rainforest in the southwestern quadrant of Brazil. It was founded in 1983 by ex-rubber tapper Sebastião Mota de Melo and a collection of followers of the religion known as "Santo Daime." These men and women were seeking to create a "New World," separating themselves from a society that was undergoing a great deal of upheaval as the period marked the initial phases of major deforestation in the Amazon. The community, therefore, offered a chance of escape from the devastation around them and the freedom to practice their religious beliefs. ''The Holy Gift,'' as it translates in Portuguese, Santo Daime is a religion that melds together popular Roman Catholicism and indigenous ayahuasca use, as well as Afro-Brazilian spirit possession, Amazonian encantaria, and most recently, New Age beliefs and concepts. Ayahuasca is a concoction of two plants, B. caapi and P. viridis, that produces psychotropic effects and has been widely consumed among indigenous tribes in the Amazon. However, in the context of Santo Daime, it has been deemed a kind of sacrament, the central force of a religious movement that has expanded from its corner in the Amazon into urban centers across Brazil and into Europe, North America, and Japan. Though maintaining a fairly small following of 10,000, Santo Daime has become a global religious movement. This thesis attempts to unravel two seemingly contradictory processes embodied in the community of Céu do Mapiá: separation and expansion. First, I outline the trajectory of the community from its initial ideals to its later entanglements with state and other international actors. Second, I trace the network of people, ideas, and goods that have become a part of Santo Daime''s international expansion. Third, I discuss the contemporary everyday rhythms in the communities and how they have been shaped by the various relationships that have developed through this expansion, positing that place is a nexus of relations.

Recent work on consumption allocations in village economies finds that idiosyncratic variation in consumption is systematically related to idiosyncratic variation in income, thus rejecting the hypothesis of full risk-pooling. We attempt to explain these observations by adding limited commitment as an impediment to risk-pooling. We provide a general dynamic model and completely characterise efficient informal insurance arrangements constrained by limited commitment, and test the model using data from from three Indian villages. We find that the model can fully explain the dynamic response of consumption to income, but that it fails to explain the distribution of consumption across households.