Most Popular Books by J. Graham

Microbial organisms often produce biologically active and chemically intriguing secondary metabolites. To isolate and characterize compounds of novel activity and structure, bioassay- guided fractionations were employed on a variety of natural products sources. Active compounds were characterized by spectroscopic analysis and X-ray diffraction methods. As a result of these studies, six projects were completed, resulting in the purification of a diverse range of compounds containing activity in a variety of assays. A coumarin and parahydroxyphenylethanol were determined to possess phytotoxic activity from fungal pathogens. Two novel C-glycosidic compounds from a bacterial plant pathogen were found to be the first low molecular weight elicitors of the hypersensitive response in plants. A verticillin of the epi-polythiodiketopiperazine class isolated from a soil fungus was discovered to be responsible for inhibition of ras farnesylation transferase. Leafcutter ants were found to be deterred by the presence of a novel sesqualterpenoid in epiphylls. Finally, inhibitors of the PDGF receptor were isolated and characterized from a lichen.

Reprint of the original, first published in 1862.

This title is part of a series of books that reflects the trend towards a core curriculum and self-directed learning. The content is restricted to the ''must know'' core information presented in a synoptic style. The diagrams that support the text are in a style that the reader can remember and reproduce in examinations. Each chapter ends with a selection of self-assessment material and full explanatory answers. These consolidate and expand on the chapter contents. - Concise synoptic (not telegraphic text). - Appropriate self-assessment material. - Only covers core, so student knows the whole book is essential. - Includes key objectives. - Contains simple and memorable diagrams for reproduction in exams. - Ideal for learning as well as examination review, specifically trying to stimulate the student into assessing his/her own knowledge. - The books in the series both complement other available major texts, but also contain enough material to stand in the own right. - Provides examination practice. - Part of co-ordinated series.

Thermodynamics is the physical science surrounding work, heat, and relationships across fundamental quantities, and situates itself near the center of multiple disciplines through its generality and timelessness. Its laws required no rewriting after the twentieth century revolutions of quantum mechanics, relativity, and solid state physics, just to name three subjects. The nine chapters of this book make appeal to thermodynamic notions and laws to get under the hood of mathematics—the language of the physical sciences—without just echoing things best said and written in math books. It takes a system to learn about another system—we all need thermometers, voltmeters, and other gadgets to get to know objects of interest. But just as critical are the numbers and functions we put to the task, however relegated they are to computers in the modern day for the heavy lifting. To be sure, mathematical representations like x = 1⁄2, 5.2, π, e, etc., and f(x) = x2, sin(x), etc., are never in physical contact with the solids, liquids, and gases that draw our attention, but they are as impacted by the same natural laws as the lab apparatus itself. This book shows how the thermodynamic laws impact our number systems. The laws affirm that we have direct access to a vanishingly small fraction of the real numbers. They further establish that the real numbers present a maximum-evolved system impacting all matters of computation, graphing, differentiation, and integration. For completeness, one of the chapters includes cases where the thermodynamic laws have little, if anything, constructive to say about representations in mathematics. This book presents a novel perspective to students and teachers in the physical sciences, biology, and mathematics, with the goal of enriching classroom and seminar hours. The chapters are self-contained and written informally, and readers with rudimentary knowledge of energy, numbers, and functions should handle the material well.

The period 1650 to 1790 was such a turbulent one for Scottish seafarers that much of this fast-flowing narrative reads like Treasure Island. Colourful characters abound in a story teeming with incident and excitement: John Paul Jones descends upon the Scottish coast creating widespread panic; press gangs prowl the coastal towns; wartime conditions turn merchantmen into privateers fighting the French, the Spanish and the American Colonists – almost anyone flying a different flag; quaintly named vessels like The Provoked Cheesemaker are on the lookout for trouble. And the stakes were high. Glasgow became wealthy through the tobacco trade. Glasgow merchantmen could beat the English ships and sail to Chesapeake Bay in record time. Eric Graham traces the development of the Scottish marine and its institutions during a formative period, when state intervention and warfare at sea in the pursuit of merchantilist goals largely determined the course of events. He charts Scotland''s frustrated attempts to join England in the Atlantic economy and so secure her prosperity – an often bitter relationship that culminated in the Darien Disaster. In the years that followed, maritime affairs were central to the move to embrace the full incorporating Act of 1707. After 1707, Scottish maritime aspirations flourished under the protection of the British Navigation Acts and the windfalls of the endemic warfare at sea.

One of the most exciting and produced American playwrights of the second half of this century, Sam Shepard''s writing career began in 1964 and continues today. This book examines the playwright''s canon first from the perspective of dramatic analysis and intertextuality in terms of theme and performance vocabulary, then from the director''s perspective in interpretation for performance. The book is useful to the scholar, the theatre professional, and the theatre goer. Shepard''s dramaturgy is analyzed both in terms of dramatic and cinematic influences and of its originality. The author examines how Shepard has synthesized these influences into the unique contemporary dramatic form which Graham terms «Metarealism.»

A hidden branch of the human family, forewarned of a global cataclysm, arises from obscurity to survive against seemingly insurmountable odds.

This book explores the remarkable information correspondences and probability structures of proteins. Correspondences are pervasive in biochemistry and bioinformatics: proteins share homologies, folding patterns, and mechanisms. Probability structures are just as paramount: folded state graphics reflect Angstrom-scale maps of electron density. The author explores protein sequences (primary structures), both individually and in sets (systems) with the help of probability and information tools. This perspective will enhance the reader’s knowledge of how an important class of molecules is designed and put to task in natural systems, and how we can approach class members in hands-on ways.

Creating the Project Office is written for managers who are searching for ways to transform their organizations into more effective and efficient project-based workplaces. As this important book reveals, there is no more effective way to make that change than to create a project office tailored to the needs of the organization. While a project office model leads to better products from projects, it is also a vehicle for generating overall organizational change -- by transforming the organization from function-based to project-based. This model incorporates projects into the very fabric of the organizational strategy and revitalizes organizations, creates competitive advantage, and increases shareholder value.

Comic drama Characters: 2 male, 4 female Interior, exterior or unit set. A warm drama played against the hatred in Northern Ireland, Remembrance charts the love that develops between a Protestant father and a Catholic mother who meet in the cemetery where their sons are buried, both victims of violence. Family members burden the courtship with personal antagonisms. "An absorbing, powerful and touching play.... A gripping account of the brutality of bigotry that knows

I have presented a theory of form and structure, the Manichean leitmotif, which deals with the ideology and psychology of racism in American fiction. Through the theoretical and textual analyses undertaken here, we have followed the peculiar origins and development of an aesthetic theory of beauty and the sublime, specifically through a focus on Samuel Gilman''s doctrinal force of contrasted extremes. Primarily through conventional rhetorical devices comprising the ascend-descend framing device and the triadic color structure, repressive attitudes conditioned by the defense of slavery and malignant images of dark humanity have undoubtedly crept into the expressive character of the literature. Without imaginative and constructive criticism, such as that offered by the theory of the Manichean leitmotif, there can be little or no conscious awareness of the continuing unconscious ideas and impulses of negation, resulting from deliberate skin-color symbolism in the literature. Whenever a reader identifies racially and culturally with certain fictional characters - - for example, Frank Norris'' Polish Jew, half-breed Mexican, Chinese cigar-maker, big mulatto, and little colored girl in McTeague; Edgar Allen Poe''s Jupiter in The gold bug; and William Dean Howells'' Rhoda in An imperative duty - - that reader runs the risk of acquiring the attributes of his or her negation. This possibility holds true with even greater devastation when similar character traits are cinematically inculcated, because the aesthetic elements of form, sound, color and motion that comprise the doctrinal force of contrasted extremes are simultaneously heard and visualized without the tediousness of reading or skimming over their designs in the narrative. The cinema, therefore, not only tends to reinforce malignant images of dark humanity, but it also surpasses the print media in intensity of perception and verisimilitude. Fundamentally, regardless of the medium, repeated and systemic impressions of the self as buffoon and as avatar of evil and death create the degrading effects of worthlessness and non-achievement. The Manichean leitmotif causes psychic revulsions in non-white readers, in at least two important respects. First, it gives a distorted view of the past, present and even future roles of dark humanity in the social and intellectual life of America, often discrediting non-white heroes and relegating race relations to those of the feudalistic miscarriages of master and slave. Such portrayals often result in ennui and in loss of initiative, eventually, to penetrate the literature for its total intellectual and emotional content. Second, non-whites become dismayed because of the historic facts of their lives, and the mythopoetics thereof, do not correspond or coincide with the perversions of imbecility, evil, and death that are rendered, time and again, in works which convey negative skin-color symbolism through the doctrinal force of contrasted extremes. For white readers, the Manichean leitmotif is a terror-inducing device which reinforces racial stereotypes and which creates a mental block to understanding non-whites. Essentially, it prevents genuine probe into the complexities and variegated dimensions of non-whites, who, as comic and tragic avatars, are seldom, if ever, integral parts of plot. Whites are often given to believe, for example, that a piano falling on a "big mulatto" with a "resounding crack," and a Jupiter or Hark climbing up a tree are merely comic relief; but such presentations, in their deeper import, reflect a distorted view of humanity and of the world in literary forms. As an ideological design, the Manichean leitmotif plays on white fears of miscegenation, and on mistaken beliefs of racial superiority. Furthermore, such a design creates the rationale that non-whites are inferior seats of sin and crime, and are objects of suspicion and detection

From a review of the first edition: '' ... impressive ... this book is likely to be read and consulted widely.'' Behaviour Research and Therapy Entirely revised and augmented with 11 new chapters, the authors provide the latest scientific validations with practical treatment guidance for professionals working with disturbed children.

This collection of blog posts shares one single girls discovery of what love is really all about through dating, relationships, and everything in between. And there are always things in between.Each experience opens the door to getting to know love-and ourselves-in the purest form.Penalty 1 - There is no love without risks.Penalty 2 - You must be who you are.Penalty 3 - You must check your baggage at the door.Penalty 4 - Strings are always attached.Penalty 5 - Sometimes you have to color outside the lines.Penalty 6 - Great sex requires great love.Penalty 7 - S**t happens and things fall apart.Penalty 8 - Go hard or go home.Contains some adult language.