New Releases by Ian Jackson

The micro Amusings of Australian author Ian Jackson suggests a definitive ''without fanfare'' approach to humour and satire. His stories and ditties sweep across different genres and subjects with a thought-provoking approach to debate and discussion. A former London resident, his narratives are ensconced deep within the heart of Hampstead, the traditional London borough that is home to some of the richest inhabitants of our planet, yet also harbours the lower orders of the population, such as the jobless man at the end of his wits who finds himself thrust into the limelight when he suddenly inherits divine spiritual aptitude. Then there is the uber ambitious estate agent hatching a plot to use counter intelligence to inject dynamism into the housing market and the erstwhile leader of a secret mystical organisation burdened by the calling to make the most important announcement of his life to his followers. Jackson also tackles domesticity with the long suffering wife wondering how to spice up her staid marriage and politics comes under the radar when a Parliamentary Senate Committee is recalled to discuss the most far reaching scientific discovery of our age. Jackson''s writing takes in spies, extra terrestrials, religion and intergalactic Superheroes in equal measure. Whether the reader is a political observer or a radical dreamer, has interest in religion or race, society or nature, conservation or the vagaries of one super power or t''other, Amusings tickles the edges of humour with its eclectic and succinct micro narratives. Subtle, laconic, surrealist and at times acerbic witticisms offer a translucent glance at generic satire, whimsically casting a glance at our post modern world.

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Hegel''s 1807 Phenomenology of Spirit is renowned for being one of the most challenging and important books in Western philosophy. Above all, it is famous for laying out a new approach to reasoning and philosophical argument, an approach that has been credited with influencing Karl Marx, Jean-Paul Sartre, and many other key modern philosophers. That approach is the so-called "Hegelian dialectic" - an open-ended sequence of reasoning and argument in which contradictory concepts generate and are incorporated into a third, more sophisticated concept. While the Phenomenology does not always clearly use this dialectical method - and it is famously one of the most difficult works of philosophy ever written - the Hegelian dialectic provides a perfect template for critical thinking reasoning skills. A hallmark of good reasoning in the construction of an argument, and the searching out of answers must necessarily consider contradictory viewpoints or evidence. For Hegel, contradiction is key: it is precisely what allows reasoning to progress. Only by incorporating and overcoming contradictions, according to his method, is it possible for thought to progress at all. While writing like Hegel might not be advisable, thinking like him can help take your reasoning to the next level.

Published in 1776, when America was teetering on the brink of war with Britain, Common Sense galvanized the colonists and George Washington''s army, influencing not only the course of the Revolutionary War, but also the resultant government.

Hegel’s 1807 Phenomenology of Spirit is renowned for being one of the most challenging and important books in Western philosophy. Above all, it is famous for laying out a new approach to reasoning and philosophical argument, an approach that has been credited with influencing Karl Marx, Jean-Paul Sartre, and many other key modern philosophers. That approach is the so-called “Hegelian dialectic” – an open-ended sequence of reasoning and argument in which contradictory concepts generate and are incorporated into a third, more sophisticated concept. While the Phenomenology does not always clearly use this dialectical method – and it is famously one of the most difficult works of philosophy ever written – the Hegelian dialectic provides a perfect template for critical thinking reasoning skills. A hallmark of good reasoning in the construction of an argument, and the searching out of answers must necessarily consider contradictory viewpoints or evidence. For Hegel, contradiction is key: it is precisely what allows reasoning to progress. Only by incorporating and overcoming contradictions, according to his method, is it possible for thought to progress at all. While writing like Hegel might not be advisable, thinking like him can help take your reasoning to the next level.

Geoffrey Parker spent 15 years writing this ambitious history of the tumultuous 17th century, a period in the grip of what historians term the General Crisis (2013).

Thomas Paine’s 1776 Common Sense has secured an unshakeable place as one of history’s most explosive and revolutionary books. A slim pamphlet published at the beginning of the American Revolution, it was so widely read that it remains the all-time best selling book in US history. An impassioned argument for American independence and for democratic government, Common Sense can claim to have helped change the face of the world more than almost any other book. But Paine’s pamphlet is also a masterclass in critical thinking, demonstrating how the reasoned construction of arguments can be reinforced by literary skill and passion. Paine is perhaps more famous as a stylist than as a constructor of arguments, but Common Sense marries the best elements of good reasoning to its polemic. Moving systematically from the origins of government, through a criticism of monarchy, and on to the possibilities for future democratic government in an independent America, Paine neatly lays out a series of persuasive reasons to fight for independence and a new form of government. Indeed, as the pamphlet’s title suggested, to do so was nothing more than ‘common sense.’

Francis Fukuyama’s controversial 1992 book The End of History and the Last Man demonstrates an important aspect of creative thinking: the ability to generate hypotheses and create novel explanations for evidence. In the case of Fukuyama’s work, the central hypothesis and explanation he put forward were not, in fact, new, but they were novel in the academic and historical context of the time. Fukuyama’s central argument was that the end of the Cold War was a symptom of, and a vital waypoint in, a teleological progression of history. Interpreting history as “teleological” is to say that it is headed towards a final state, or end point: a state in which matters will reach an equilibrium in which things are as good as they can get. For Fukuyama, this would mean the end of “mankind’s ideological evolution and the universalization of Western liberal democracy as the final form of human government”. This grand theory, which sought to explain the end of the Cold War through a single overarching hypothesis, made the novel step of resurrecting the German philosopher G.W.F. Hegel’s theory of history – which had long been ignored by practical historians and political philosophers – and applying it to current events.

John Locke’s 1689 Two Treatises of Government is a key text in the history of political theory – one whose influence remains marked on modern politics, the American Constitution and beyond. Two Treatises is more than a seminal work on the nature and legitimacy of government. It is also a masterclass in two key critical thinking skills: evaluation and reasoning. Evaluation is all about judging and assessing arguments – asking how relevant, adequate and convincing they are. And, at its heart, the first of Locke’s two treatises is pure evaluation: a long and incisive dissection of a treatise on the arguments in Sir Robert Filmer’s Patriarcha. Filmer’s book had defended the doctrine that kings were absolute rulers whose legitimacy came directly from God (the so-called “divine right of kings”), basing his arguments on Biblical explanations and evidence. Locke carefully rebutted Filmer’s arguments, on their own terms, by reference to both the Bible and to recorded history. Finding Filmer’s evidence either to be insufficient or unacceptable, Locke concluded that his argument for patriarchy was weak to the point of invalidity. In the second of Locke’s treatises, the author goes on to construct his own argument concerning the sources of legitimate power, and the nature of that power. Carefully building his own argument from a logical consideration of man in “the state of nature”, Locke creates a convincing argument that civilised society should be based on natural human rights and the social contract.

David Hume’s Dialogues Concerning Natural Religion is a philosophical classic that displays a powerful mastery of the critical thinking skills of reasoning and evaluation. Hume’s subject, the question of the existence and possible nature of God, was, and still is, a persistent topic of philosophical and theological debate. What makes Hume’s text a classic of reasoning, though, is less what he says, than how he says it. As he noted in his preface to the book, the question of ‘natural religion’ was unanswerable: so ‘obscure and uncertain’ that ‘human reason can reach no fixed determination with regard to it.’ Hume chose, as a result, to cast his thoughts on the topic in the form of a dialogue – allowing different points of view to be reasoned out, evaluated and answered by different characters. Considering and judging different or opposing points of view, as Hume’s characters do, is an important part of reasoning, and is vital to building strong persuasive arguments. Even if, as Hume suggests, there can be no final answer to what a god might be like, Dialogues Concerning Natural Religion shows high-level reasoning and evaluation at their best.

The eighteenth-century philosopher Immanuel Kant is as daunting as he is influential: widely considered to be not only one of the most challenging thinkers of all time, but also one of the most important. His Religion Within the Boundaries of Mere Reason takes on two of his central preoccupations – the reasoning powers of the human mind, and religion – and applies the full force of his reasoning abilities to consider the relationship between them. In critical thinking, reasoning is all about constructing arguments: arguments that are persuasive, systematic, comprehensive, and well-evidenced. And any examination involves stripping reasoning back to its barest essentials and attempting to get at the nature of the world by asking what we can know about God and morality from the power of our minds alone. Beginning from the axiom that God is, by definition, unknowable, Kant reasons that it is humans who bear the responsibility of creating the Kingdom of God. This, he suggests, we can do by acting morally in the world we experience – with a morality that can be shaped by reason alone. Dense and challenging, but closely and persuasively reasoned, Kant’s case for human responsibility shows reasoning skills at their most impressive.

At 30, Alex Kingbridge never new his parents. He spent his normal day doing electrical work on farm machinery. When he finds that his father had left money to himself and a vague list of people across Australia, he is engaged by a law firm to track them down. The clues that link them all come from a string of unique spiral wooden staircases that his father had built in different towns from thirty years before. Find the missing staircase and he has a chance to find the missing person.Alex goes on an adventure that traverses Australia and New Zealand and meets a lot of interesting people along the way. Only with his special methods of problem solving and a little luck can he complete his mission.

Humorous watercolor drawing and vignette by Ian Jackson concerning the deletion of the word "scylline" from a quotation of Eric Korn in the second edition of Chamberpot & Motherfuck: the price-codes of the book trade, as proposed by publisher Bruce McKittrick.

The North Kent Marshes can be a cold, damp, lonely place or a bright, warm refuge from the urban hurly-burly. When war threatened the army and navy mounted guard on their rivers, creeks and foreshores. In times past few would venture into their disease ridden swamps. Haunted by smugglers the saltings and seaways played host to preventive men and coastguards. Their savage beauty inspired many writers and artists including Dickens and Turner. They have grown the crops and raised the cattle and sheep to feed the London market. The marshland nature reserves are internationally important for the future well-being and survival of breeding and migratory birds. In these days of industrial and environmental peril the wilderness on London''s doorstep is threatened as never before. The history of the marshes and their people has rarely been told.

The betrayal, death and resurrection of Jesus Christ told in verse with this story also presented as a short play with the text in play-script format.

Story of the Jacobovitch family from Stazow in Russian occupied Poland and their story of Samuel and his family in early 20th century London''s East End. The conditions and what was happening.

The combination of severe ocular and distal limb malformations is rare. Ophthalmo-acromelic syndrome (OAS; MIM 206920) is characterised by anophthalmia with lower limb oligodactyly. To date 40 cases of this autosomal recessive disorder have been reported. Genome-wide analysis of ~10,000 SNPs typed on two apparently unrelated families - comprising a total of three affected individuals, four unaffected siblings and their consanguineous parents - identified a large region of overlapping autozygosity on chromosome 14q. Adding data from a third consanguineous family gave a combined LOD score of 5 with no evidence of locus heterogeneity. Collaborative data from a further 6 individuals refined the critical interval to a 3.4 Mb region on chromosome14:69,652,605-73,059,612 Mb. To sequence all 19 known protein-coding genes in the region, the 238 exons were ranked by evolutionary sequence conservation and divided equally between the Edinburgh and Nijmegen groups. Complete sequence coverage has been obtained for 61% of the "Edinburgh" exons but no potentially causative mutations have been identified. Further mutation analysis of the OAS locus is on-going. Mice homozygous for the X-ray induced Mp mutation were reportedly anophthalmic with hind limb oligodactyly and thus represented a potential model for human OAS. This line was rederived in Edinburgh and phenotypic analysis of Mp/Mp homozygotes showed runting, malformed pinnae with microphthalmia but not anophthalmia. The apparent hind-limb oligodactyly was due to osseous syndactyly. Mp heterozygotes had milder microphthalmia and pinnae deformities, but lacked the syndactyly. In both heterozygotes and homozygotes the eye malformations were fully penetrant, pan-ocular and characterised by failure of both the ciliary apparatus and vitreous body to form and abnormal retinal lamination. Genome-wide microsatellite marker analysis showed linkage of the Mp phenotype to chromosome 18. Fbn2 mapped within the linkage interval and was a good candidate for Mp based on the finding of hind limb osseous syndactyly in Fbn2-null mice. However, Fbn2-null mice have no eye phenotype. 3''-RACE identified that Mp was as a 660 kb inversion affecting the 3''-regions of Fbn2 and the adjacent gene Isoc1. This created two aberrant reciprocal fusion transcripts: Fbn2 exons 1-63 are fused to Isoc1 exon 5; and Isoc1 exons 1-4 are fused to Fbn2 exons 64-65. This predicts nonsense-mediated decay of the Isoc1 Mp transcript and production of a truncated Fbn2 Mp protein. Ocular development was analysed in homozygote and wild type embryos to define the basis of the "worse than null phenotype" seen in Mp mice. RNA in situ hybridisations (ISH) failed to detect expression of Isoc1 in the embryonic eye. In contrast, normal expression of Fbn2 in the ciliary body and retina was consistent with the Mp phenotype. A combination of EM and immunocytochemistry showed that truncated Fbn2 (Fbn2Mp) was retained within the ER. Fbn2Mp co-localised with markers of ER stress: Grp78 expression and UPR-specific Xbp1 splicing. Signalling by Wnt2b is thought to be critical for ciliary development and Lef1, a Wnt-responsive transcription factor, showed increased and ectopic ocular expression in the region affected by ER stress. Sox2 is a direct transcriptional target of Lef1 and we observed apparent ectopic expression of Sox2 in the ciliary body. Throughout the developing retina in mutant embryos we also observed individual cells that were ectopically expressing the transcription factor Chx10 and other cells expressing the apoptotic marker Activated- Caspase-3. The apoptotic marker did not specifically co-localise with Fbn2Mp. Taken together, these findings suggest that the ocular malformations in Mp are a direct result of the ER stress induced by Fbn2Mp in a specific group of cells in the early ciliary body. The ER stress presumably halts post-translational modification of a developmentally critical signaling molecule, possibly Wnt2b, which happens to be expressed in the same cells. We have termed the resulting pathological mechanism a synodiporic effect (synodiporia = the ones walking the street together or fellow travellers). Such effects may have significant implications for human genetic disease analysis, and may provide an explanation for other "worse than null" mutations.

Describes the history of Ancient Egypt, from its origins as a group of settlements along the banks of the Nile, to its transformation into one of the world''s earliest and greatest civilizations.

Ian Jackson draws on his inside knowledge of the rapidly changing market in nukenomics. He describes the major trends and market forces that are actively shaping the future development of the nuclear industry today, by explaining not just what things are happening but, more fundamentally, why.