Most Popular Books by David FRENCH

Shapes of Things contains a series of interviews with bassist and producer Paul Samwell-Smith discussing the first decade of his career. Paul got his start in the pioneering 1960s band the Yardbirds, working alongside guitarists Eric Clapton and Jeff Beck. He led the group''s musical evolution during the group''s peak years, moving from hard-hitting covers of American blues and R''n''B songs to a string of influential Top Ten singles, including "For Your Love," "Heart Full of Soul," "Evil Hearted You/Still I''m Sad," "Shapes of Things," and "Over, Under, Sideways, Down." After leaving the Yardbirds in 1966 (Jimmy Page was his replacement), Paul became a highly successful producer, especially known for his work with Cat Stevens/Yusuf and Carly Simon. In these interviews, Paul talks about life as a pop star at the height of Beatlemania, learning the ropes and coming into his own as a producer, and the personal crises that twice forced him to step back from the rock''n''roll life. Along the way, he provides an intimate look at recording the Yardbirds, Yusuf, and Carly Simon, as well as encounters with artists from Jimmy Reed and Sonny Boy Williamson II, to Cyril Davies, the Beatles, Peter and Gordon, Jackie DeShannon, the Rolling Stones, Murry Head, Paul Simon, and more.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

The dysregulation of pro-inflammatory cytokines as a result of stress exposure has become widely implicated in the complex etiology of depression. Patients with depression have been shown to have elevated levels of pro-inflammatory cytokines both in plasma and cerebral spinal fluid. During times of stress pro-inflammatory cytokines are primarily regulated by glucocorticoids and catecholamines that work in opposition to one another to inhibit (glucocorticoid receptor) or stimulate (beta-adrenergic receptor) pro-inflammatory cytokine production. While chronic stress can lead to heightened levels of both glucocorticoids and catecholamines, it is not known how the dysregulation of these systems affect the regulation of pro-inflammatory cytokines. This dissertation focused its work through three aims. Aim 1 explored norepinephrine''s regulation of microglial pro-inflammatory cytokines. Aim 2 examined sex differences in the regulation of brain IL-1 beta by glucocorticoids and catecholamines following chronic stress. Finally, aim 3 sought to uncover glucocorticoids effect on norepinephrine turnover. Together, these aims help to better understand how chronic stress alters the regulation of brain pro-inflammatory cytokines with implications for depression.