New Releases by Daniel Kraus

Daniel Kraus is the author of Athanasia (2025), Angel Down (2025), The Joker's on You (2025), Season's Eatings (2024), Monster Variations (2024).

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Athanasia

release date: Oct 07, 2025
Athanasia
Watchmen meets Unbreakable in the darkly disturbing supernatural tale, ATHANASIA, where the heroic dead bleed power into the ground … only to be unearthed by a down-on-her-luck young woman to unforeseeable consequences. Some secrets are best left buried. Forrest Molson is going nowhere. One year out of high school -- and one year into sobriety -- she''s working with her father as assistant groundskeeper at Athanasia Cemetery, the final resting place of fallen members of the Dynamic Guild, Venture City''s resident superheroes. At her lowest point, Forrest discovers Athanasia''s darkest secret. At night, the cemetery soil bleeds a substance created from the spectacular substances that ooze from rotting superheroes. This ooze becomes Forrest''s new drug -- and she''s intent on using her unpredictable new powers to be judge, jury, and executioner of Venture City''s evil citizens. But as she loses her mind to her new addiction, she inches closer to becoming the most evil of all. ATHANASIA is a superhero story seen through the darkest lens. From New York Times bestselling author Daniel Kraus (The Autumnal, Whalefall, The Shape of Water) and rising star artist Dani! For fans of the graphic novels Black Hammer (Jeff LeMire/Dean Ormston), Watchmen (Alan Moore/Dave Gibbons), The Crow (James O’Barr +Film), Kingdom Come (Mark Waid/Alex Ross), Batman: The Killing Joke (Alan Moore/Brian Bolland), The Boys (Garth Ennis/Darick Roberson), The Authority (Warren Ellis/Bryan Hitch); the films Darkman, Chronicle, and Unbreakable and the novels Alter Ego (Alex Segura), Secret Identity (Alex Segura),V.E. Schwab’s Villains series (Vicious and Vengeful), and Jennifer Estep’s Elemental Assassin series.

Angel Down

release date: Jul 29, 2025
Angel Down
The critically acclaimed author of the “crazily enjoyable” (The New York Times) Whalefall returns with an immersive, cinematic novel about five World War I soldiers who stumble upon a fallen angel that could hold the key to ending the war. Private Cyril Bagger has managed to survive the unspeakable horrors of the Great War through his wits and deception, swindling fellow soldiers at every opportunity. But his survival instincts are put to the ultimate test when he and four other grunts are given a deadly mission: venture into the perilous No Man’s Land to euthanize a wounded comrade. What they find amid the ruined battlefield, however, is not a man in need of mercy but a fallen angel, seemingly struck down by artillery fire. This celestial being may hold the key to ending the brutal conflict, but only if the soldiers can suppress their individual desires and work together. As jealousy, greed, and paranoia take hold, the group is torn apart by their inner demons, threatening to turn their angelic encounter into a descent into hell. Angel Down plunges you into the heart of World War I and weaves a polyphonic tale of survival, supernatural wonder, and moral conflict.

The Joker's on You

release date: Jan 01, 2025
The Joker's on You
"The Graveyard Girls face off against a sentient house while they struggle to keep their friendship alive"--

Season's Eatings

release date: Sep 17, 2024
Season's Eatings
The Graveyard Girls navigate celebrity psychics, messages from beyond the grave, and the continued mystery of Silas Hoke’s missing bones in this devouring third installment by New York Times bestselling authors Lisi Harrison and Daniel Kraus. It’s the holiday season, but the Graveyard Girls are feeling the wrong kind of spirit . . . Gemma is struggling to save the Spirit Sanctuary, while Whisper is reeling from her father’s recent engagement announcement to Paisley’s mother. Zuzu has taken on the assignment of town ghost whisperer, Frannie is looking for drama in her drama-less life, and Sophie is being haunted by a possessed doll. And through it all, the girls are getting electrifying messages from beyond the grave that may lead them to Silas Hoke’s missing bones. For a not-so-merry fright, Gemma tells a deliciously creepy tale that takes the lesson of "be careful what you wish for” to a whole new level. Fans of author Lisi Harrison’s Monster High books will enjoy this new entry in the Graveyard Girls series of mystery books for kids. Anyone looking for scary books for 8–12-year-old-girls will find exactly what they need in this thrilling next chapter in the Graveyard Girls series.

Monster Variations

release date: Jun 28, 2024
Monster Variations
FINALLY RE-RELEASING, THIS 15 YEAR ANNIVERSARY EDITION COMES WITH A BRAND NEW INTRODUCTION! Someone is killing boys in a small town. The murder weapon is a truck, and the only protection is a curfew enacted to keep kids off the streets. But it''s summer-and that alone is worth the risk of staying out late for James, Willie, and Reggie. Willie, who lost his arm in the first hit-and-run attack, finds it hard to keep up with his two best friends as they leave childhood behind. All of them are changing, hounded by their parents, hunted by the killer, and haunted by the "monster," a dead thing that guards the dangerous gateway between youth and manhood. But that''s not all: shadowing the boys everywhere is Mel Herman, the mysterious and brilliant bully whose dark secrets may hold the key to their survival. As the summer burns away, these forces collide, and it will take compassion, brains, and guts for the boys to overcome their demons-and not become monsters themselves. In this chilling and poignant debut novel, NYT bestseller Daniel Kraus deftly explores the choices boys grapple with and the revelations that occur as they become men. "Utterly unique from the very first line." -JOSHUA FERRIS, award winning author of Then We Came to the End "Beneath the terror and the thrills, there is truth in this haunting tale. It pierced my heart straight through." -LAUREN MYRACLE, NYT bestselling author of the Internet Girls series.

The Cemeterians

release date: Apr 23, 2024
The Cemeterians
The X-Files meets Wake the Bones in THE CEMETERIANS: The Complete Series, an eerie, genre-blending story filled with horror, magic, mystery, fantasy, darkness, and bones that grow where they shouldn’t. Some things won’t stay buried. After human bones begin growing inside inanimate objects all across the globe, a renegade scientist and brilliant theologian delve into the cemeteries where the bones originated, discovering an otherworldly force tired of being buried in darkness. The Cemeterians will chill you to the bone. Written by New York Times bestselling author Daniel Kraus (The Shape of Water, Trollhunters (both with Guillermo del Toro), Rotters, Graveyard Girls, The Living Dead (with George Romero) The Teddies Saga, Whalefall (his latest), and The Autumnal (for Vault Comics)) and illustrated by critically-acclaimed and atmospheric artist Maan House (Witchblade, Krampus, Project Blue Book). For fans of The X-Files, Poltergeist, Glitch, Wake the Bones (Elizabeth Kilcoyne), Rotters, Graveyard Girls, and The Living Dead (Daniel Kraus), Pet Sematary (Stephen King), Cemetery Girl (Charlaine Harris & Christopher Golden), and The Resurrectionist of Caligo (Wendy Trimboli & Alicia Zaloga) PRAISE FOR THE CEMETERIANS: The Cemeterians (Nightfall: Double Feature) was named one of the “Horror comics to watch for in 2023” – Fangoria “Tactile, fearsome, haunting — this is horror of the finest quality.” – Multiversity Comics “Transformative, boundary-pushing horror.” – Gatecrashers

Whalefall - Im Wal gefangen

release date: Jan 01, 2024
Whalefall - Im Wal gefangen
Obwohl es ein aussichtsloses Unterfangen ist, hat sich Jay Gardiner an der Pazifikküste vor Monastery Beach auf die Suche nach den sterblichen Überresten seines Vaters gemacht. Er glaubt, dass es die einzige Möglichkeit ist, seine Schuldgefühle loszuwerden, die er seit dem Selbstmord seines Vaters mit sich herumträgt. Bei einem Tauchgang wird er von den Tentakeln eines Riesenkalmars erfasst, der kurz darauf von einem Pottwal auf der Suche nach Futter angegriffen wird. Gemeinsam landen sie in einem der vier Mägen des riesigen Wals ... Jay hat nur eine Stunde Zeit, bevor ihm der Sauerstoff ausgeht - eine Stunde, um seine Dämonen zu besiegen und aus dem Bauch des Wals zu entkommen. Ein wissenschaftlich exakter Thriller, der in einer absurd unwahrscheinlichen Umgebung spielt. Ein emotionales und wahnsinnig unterhaltsames Abenteuer. Doch der Star des Buches ist eindeutig der Wal - gewaltig, unergründlich und intelligent. Und er ist sich, wie Jay, seiner Sterblichkeit sehr bewusst. Daniel Kraus, der mit Guillermo del Toro die Romanversion des Films The Shape of Water schrieb, schildert die Rätsel der Unterwasserwelt mit der Strenge eines Wissenschaftlers und der Sensibilität eines Dichters. Booklist: »Eine bewegende Charakterstudie, getarnt als fesselnder, kinoreifer Überlebensthriller ... Das Tempo ist unerbittlich, die Ehrfurcht verblüffend und die Spannung erdrückend ...« Gillian Flynn: »Außergewöhnlich großartig. Whalefall ist wirklich ein wunderschöner Roman - ein Must Read über das Meer, die Demut und die bitteren Beziehungen zwischen Vätern und Söhnen.« Daniel Kraus ist Bestsellerautor zahlreicher Romane, die in über 20 Sprachen übersetzt wurden, darunter THE LIVING DEAD, den er gemeinsam mit dem legendären Regisseur George A. Romero schrieb. Zusammen mit Guillermo del Toro schuf er THE SHAPE OF WATER, die Verfilmung wurde mit einem Oscar prämiert. Ebenfalls mit del Toro verfasste Kraus den Roman TROLLHUNTERS, der die Vorlage bildete für die mit dem Emmy ausgezeichnete Netflix-Serie. Er lebt mit seiner Frau in Chicago. Besucht Daniel auf seiner Website: danielkraus.com

Creepshow: Holiday Special 2023 (One Shot)

release date: Dec 06, 2023
Creepshow: Holiday Special 2023 (One Shot)
CREEPSHOW is here to put the fear in your cheer! You’ve heard of Santa, you’ve heard of Krampus, but have you ever heard of “The Christmas Man”? Witness the birth of a new horrifying holiday classic from DANIEL DONT CALL ME SANTA KRAUS (The Shape of Water) and jolly JONATHAN WAYSHAK (Skin Crawl)! Then, jovial JAMES ASMUS (Survival Street, Rick Morty) and lively LETIZIA CADONICI (House of Slaughter) deliver a cautionary tale about stealing the wrong parcel in “Package Thief.”

Canadian Mountain Assessment

release date: Nov 01, 2023
Canadian Mountain Assessment
The Canadian Mountain Assessment provides a first-of-its-kind look at what we know, do not know, and need to know about mountain systems in Canada. The assessment is based on insights from First Nations, Métis, and Inuit knowledges of mountains, as well as findings from an extensive assessment of pertinent academic literature. Its inclusive knowledge co-creation approach brings these multiple forms of evidence together in ways that enhance our collective understanding of mountains in Canada, while also respecting and maintaining the integrity of different knowledge systems. The Canadian Mountain Assessment is a text-based document, but also includes a variety of visual materials as well as access to video recordings of oral knowledges shared by Indigenous individuals from mountain areas in Canada. The assessment is the result of over three years of work, during which time the initiative played an important role in connecting and cultivating relationships between mountain knowledge holders from across Canada. It is the outcome of contributions from more than 80 Indigenous and non-Indigenous individuals and contains six chapters: Introduction Mountain Environments Mountains as Homelands Gifts of the Mountains Mountains Under Pressure Desirable Mountain Futures By way of these chapters, the Canadian Mountain Assessment aims to enhance appreciation for the diversity and significance of mountains in Canada, to clarify challenges and opportunities for mountain systems in the country, and to motivate and inform new research, relationships, and actions that support the realization of desirable mountain futures. More broadly, the Canadian Mountain Assessment provides insights into applied reconciliation efforts in a knowledge assessment context and seeks to inspire similar knowledge co-creation efforts in and beyond Canada.

The Ghost That Ate Us

release date: Oct 09, 2023
The Ghost That Ate Us
You remember the brutal crime, don’t you? Maybe you read about it on Twitter. Maybe a friend sent you a news clip. Maybe you saw it on an episode of Spectral Journeys that night you were flipping through channels, unable to sleep. Maybe after reading the true story, you won’t ever sleep again. On June 1, 2017, six people were killed at a Burger City franchise off I-80 near Jonny, Iowa. It was the bizarre and gruesome conclusion to nine months of alleged paranormal activity at the fast-food joint—events popularly known as “the Burger City Poltergeist. ” The story inspired Facebook memes, Twitter hashtags, Buzzfeed listicles, Saturday Night Live sketches, and more. But the case was never much more than a punchline...until bestselling writer Daniel Kraus (The Shape of Water, The Living Dead) decided to head to Iowa to dig up what really happened. Presented here is the definitive story of “the most exhaustively documented haunting in history,” including—for the first time ever—interviews with every living survivor of the tragedy. The employees of Burger City were a family. They loved one another. At least, at the beginning. But love can make you do unspeakable things.

Scream for the Camera

release date: Oct 03, 2023
Scream for the Camera
The second entry in the slightly scary, extremely addictive contemporary middle-grade series from New York Times bestselling authors Lisi Harrison and Daniel Kraus—perfect for fans of scary stories for kids, like R. L. Stine’s Goosebumps, or books for preteens, like Ann M. Martin’s The Babysitters Club. It’s been a month since the events of 1-2-3-4, I Declare a Thumb War, when the Graveyard Girls—Gemma, Whisper, Sophie, Frannie, and Zuzu—discovered Silas Hoke’s empty grave. A month, and no answers. That changes when messages from the other side start to creep up on the Graveyard Girls. Gemma’s good-luck charm. The skull in Whisper’s spilled milk. Sophie’s vanishing phone. Frannie’s theater curse. And Zuzu’s possessed Jōurnal. Who is trying to reach them . . . and why? The good news: There might be one person with some answers. The bad news: She’s a mortician . . . with a deadly secret. Speaking of bad news, straight-A Sophie is quickly sliding down the scale to becoming a B-flat friend. She is spending way more time hanging out with “Danger Me” and way less time with the Graveyard Girls and her schoolwork. Will her scary story be enough to win back her pals, or will her picture-perfect life become the ultimate photo bomb? Fans of author Lisi Harrison’s Monster High books will enjoy this new entry in the Graveyard Girls series of mystery books for kids. Anyone looking for scary books for 10-year-old girls will find exactly what they need in this thrilling sequel to 1-2-3-4, I Declare a Thumb War.

Trojan

release date: Jul 18, 2023
Trojan
In a world where mankind lives side by side with creatures of legend and myth, humanity turned out to be the real monsters, fearing, hating, and exploiting the race of magical Fey they once revered. Into this twisted fairy tale world steps Nessa, a young woman harboring dark secrets and an even darker agenda—infiltrating the criminal underworld that stages Fey torture videos for streaming on the darkweb. TROJAN is a fantasy thriller full of wonder and horror in equal measure! Once upon a time, we lived alongside Legends. Creatures of myth. Centaurs, fauns, gorgons, kelpies, gnomes, and more. They were spectacular. Majestic. Powerful. Peaceful. Pure. In comparison, we were ugly. Weak. Warmongering. Rotten. Is it any wonder we could not live alongside them any longer? After driving these Legends to the fringes of society, an uglier form of mythos takes shape in the form of rumors of live snuff shows for dark web high rollers. When a mysterious young woman, Nessa, enlists the help of a hacker to take a tour of the grisliest corners of the Dark Web, she sets in motion a war between those who peddle to mankind’s darkest fantasies and a world that transcends imagination. TROJAN is a fantasy thriller full of wonder and horror in equal measure.

Exumados

release date: Jul 13, 2023
Exumados
Uma obra inquietante que revela a sujeira em nossas mãos Roubo de túmulos. Que tipo de monstro faria uma coisa dessas? É verdade que Leonardo da Vinci fez isso, Shakespeare escreveu sobre isso e os “homens da ressurreição” da Escócia do século XIX praticamente transformaram isso em arte. Mas nada disso importa para Joey Crouch, um menino de 16 anos que tira boas notas, toca na banda da escola e procura não entrar em brigas. Sua calmaria é arrebatada por uma tragédia que o força a deixar tudo o que lhe é familiar para trás e viver com um pai que jurava não existir. E, com isso, novos limites são ultrapassados. Prepare-se para desenterrar sentimentos apodrecidos que jazem em uma cova dentro de nós. Exumados, novo livro da Macabra em parceria com a DarkSide Books, é uma obra inquietante que mergulha os leitores em um mundo obscuro e visceral, e nos leva a questionar os limites da moralidade. A trama magistral de Daniel Kraus e os personagens inesquecíveis fazem de Exumados um épico comovente, aterrorizante e não convencional sobre pais e filhos, laços familiares complexos, tabus e o espectro sempre presente da mortalidade. Com uma escrita poderosa, Daniel Kraus — escritor já conhecido dos leitores brasileiros por conta da novelização do filme A Forma da Água, que deu a Guillermo del Toro o Oscar de Melhor Filme em 2018 — explora os horrores da natureza humana, e estabelece um novo patamar no mundo do suspense e do horror. O livro foi vencedor do Odyssey Award em 2012 e finalista do Bram Stoker Award no mesmo ano. A Colheita Macabra na DarkSide Books A Macabra Filmes e a DarkSide® Books selaram um pacto eterno e inauguraram, no início de 2020, o selo Macabra para apresentar livros e quadrinhos transgressores ao público brasileiro. Casa de obras como o clássico perturbador A Garota da Casa ao Lado e a icônica coleção Livros de Sangue, de Clive Barker, a Macabra apresenta ao público um livro capaz de revirar as suas entranhas. A fazenda está pronta para uma nova temporada com seus leitores macabros.

Year Zero, Volume 0

release date: Apr 26, 2023
Year Zero, Volume 0
In this action-packed prelude to the hit series, acclaimed horror writer Daniel Kraus (George Romero’s The Living Dead, The Autumnal) unveils four globe-spanning tales from the earliest days of the zombie apocalypse when even the wildest rumors couldn’t measure up to the horror to come. A streetwise Russian cop patrols the back alleys of the opportunistic black market that emerges in response to the crisis…a North Korean soldier observes strange happenings on the DMZ…An E.R. nurse in the rural South fights to protect her hospital from threats without and within…A transgender flight attendant who has observed disturbing clues as she crisscrosses the globe keeps a wary eye on the passenger in seat 23C.

Trojan #4

release date: Apr 26, 2023
Trojan #4
Once upon a time, we lived alongside Legends. Creatures of myth. Centaurs, fauns, gorgons, kelpies, gnomes, and more. They were spectacular. Majestic. Powerful. Peaceful. Pure. In comparison, we were ugly. Weak. Warmongering. Rotten. Is it any wonder we could not live alongside them any longer? After driving these Legends to the fringes of society, an uglier form of mythos takes shape in the form of rumors of live snuff shows for dark web high rollers. When a mysterious young woman, Nessa, enlists the help of a hacker to take a tour of the grisliest corners of the Dark Web, she sets in motion a war between those who peddle to mankind’s darkest fantasies and a world that transcends imagination. Trojan is fantasy thriller full of wonder and horror in equal measure. In this concluding issue, Nessa goes live in what might be the final appearance of her life.

Year Zero Vol. 0

release date: Apr 18, 2023
Year Zero Vol. 0
YEAR ZERO chronicles the aftermath of a worldwide zombie plague that affects the entire planet. See how everyday people from all walks of life try to survive in this new world where the dead eat the living, and ask yourself: "Where were YOU when the LIVES went out?!" In this action-packed prelude to the hit series, acclaimed horror writer Daniel Kraus (George Romero’s The Living Dead, The Autumnal) unveils four globe-spanning tales from the earliest days of the zombie apocalypse when even the wildest rumors couldn’t measure up to the horror to come. A streetwise Russian cop patrols the back alleys of the opportunistic black market that emerges in response to the crisis…a North Korean soldier observes strange happenings on the DMZ…An E.R. nurse in the rural South fights to protect her hospital from threats without and within…A transgender flight attendant who has observed disturbing clues as she crisscrosses the globe keeps a wary eye on the passenger in seat 23C.

Trojan #3

release date: Mar 15, 2023
Trojan #3
Once upon a time, we lived alongside Legends. Creatures of myth. Centaurs, fauns, gorgons, kelpies, gnomes, and more. They were spectacular. Majestic. Powerful. Peaceful. Pure. In comparison, we were ugly. Weak. Warmongering. Rotten. Is it any wonder we could not live alongside them any longer? After driving these Legends to the fringes of society, an uglier form of mythos takes shape in the form of rumors of live snuff shows for dark web high rollers. When a mysterious young woman, Nessa, enlists the help of a hacker to take a tour of the grisliest corners of the Dark Web, she sets in motion a war between those who peddle to mankind’s darkest fantasies and a world that transcends imagination. Trojan is fantasy thriller full of wonder and horror in equal measure.

Year Zero Vol.0 #5

release date: Feb 22, 2023
Year Zero Vol.0 #5
In this action-packed prelude to the hit series, acclaimed horror writer Daniel Kraus (George Romero’s The Living Dead, The Autumnal) unveils four globe-spanning tales from the earliest days of the zombie apocalypse when even the wildest rumors couldn’t measure up to the horror to come. A streetwise Russian cop patrols the back alleys of the opportunistic black market that emerges in response to the crisis…a North Korean soldier observes strange happenings on the DMZ…An E.R. nurse in the rural South fights to protect her hospital from threats without and within…A transgender flight attendant who has observed disturbing clues as she crisscrosses the globe keeps a wary eye on the passenger in seat 23C. See how the end of the world as we know it began in this climactic issue!

Trojan #2

release date: Feb 15, 2023
Trojan #2
Once upon a time, we lived alongside Legends. Creatures of myth. Centaurs, fauns, gorgons, kelpies, gnomes, and more. They were spectacular. Majestic. Powerful. Peaceful. Pure. In comparison, we were ugly. Weak. Warmongering. Rotten. Is it any wonder we could not live alongside them any longer? After driving these Legends to the fringes of society, an uglier form of mythos takes shape in the form of rumors of live snuff shows for dark web high rollers. When a mysterious young woman, Nessa, enlists the help of a hacker to take a tour of the grisliest corners of the Dark Web, she sets in motion a war between those who peddle to mankind’s darkest fantasies and a world that transcends imagination. Trojan is fantasy thriller full of wonder and horror in equal measure.

They Set the Fire

release date: Jan 10, 2023
They Set the Fire
At once darkly suspenseful and heartfelt with stunning spot art from illustrator Rovina Cai, this trilogy finale of New York Times-bestselling author Daniel Kraus''s action-packed The Teddies Saga is perfect for fans of Victoria Schwab, Katherine Arden, and Holly Black. An Indie Next Pick! After searching so long for a place to call home, the daring teddies–clever Buddy, shrewd Sunny, fearless Nothing, and wise Reginald–find few answers at the place where they were created, Furrington Industries. But with a new friend—a teddy of legend!—the teddies head back into the dangerous world to seek the secrets of their creation. Soon the teddies find themselves surrounded by people who hated them, and discover that the founder of Furrington Industries, known as the Suit, is on trial for an unknown crime. Left reeling but determined, Buddy leads his friends–those that survive–through the protestors that line the streets outside and into the bowels of the courthouse . . . where they’ll find out the true, incendiary reason the teddies were thrown away.

Trojan #1

release date: Jan 04, 2023
Trojan #1
Once upon a time, we lived alongside Legends. Creatures of myth. Centaurs, fauns, gorgons, kelpies, gnomes, and more. They were spectacular. Majestic. Powerful. Peaceful. Pure. In comparison, we were ugly. Weak. Warmongering. Rotten. Is it any wonder we could not live alongside them any longer? After driving these Legends to the fringes of society, an uglier form of mythos takes shape in the form of rumors of live snuff shows for dark web high rollers. When a mysterious young woman, Nessa, enlists the help of a hacker to take a tour of the grisliest corners of the Dark Web, she sets in motion a war between those who peddle to mankind’s darkest fantasies and a world that transcends imagination. Trojan is fantasy thriller full of wonder and horror in equal measure.

Multiparametric Magnetic Resonance Imaging for Radiation Therapy Response Monitoring in Soft Tissue Sarcomas: a Histology and MRI Co-registration Algorithm

release date: Jan 01, 2023
Multiparametric Magnetic Resonance Imaging for Radiation Therapy Response Monitoring in Soft Tissue Sarcomas: a Histology and MRI Co-registration Algorithm
Abstract: Rationale: To establish a spatially exact co-registration procedure between in vivo multiparametric magnetic resonance imaging (mpMRI) and (immuno)histopathology of soft tissue sarcomas (STS) to identify imaging parameters that reflect radiation therapy response of STS. Methods: The mpMRI-Protocol included diffusion-weighted (DWI), intravoxel-incoherent motion (IVIM), and dynamic contrast-enhancing (DCE) imaging. The resection specimen was embedded in 6.5% agarose after initial fixation in formalin. To ensure identical alignment of histopathological sectioning and in vivo imaging, an ex vivo MRI scan of the specimen was rigidly co-registered with the in vivo mpMRI. The deviating angulation of the specimen to the in vivo location of the tumor was determined. The agarose block was trimmed accordingly. A second ex vivo MRI in a dedicated localizer with a 4 mm grid was performed, which was matched to a custom-built sectioning machine. Microtomy sections were stained with hematoxylin and eosin. Immunohistochemical staining was performed with anti-ALDH1A1 antibodies as a radioresistance and anti-MIB1 antibodies as a proliferation marker. Fusion of the digitized microtomy sections with the in vivo mpMRI was accomplished through nonrigid co-registration to the in vivo mpMRI. Co-registration accuracy was qualitatively assessed by visual assessment and quantitatively evaluated by computing target registration errors (TRE). Results: The study sample comprised nine tumor sections from three STS patients. Visual assessment after nonrigid co-registration showed a strong morphological correlation of the histopathological specimens with ex vivo MRI and in vivo mpMRI after neoadjuvant radiation therapy. Quantitative assessment of the co-registration procedure using TRE analysis of different pairs of pathology and MRI sections revealed highly accurate structural alignment, with a total median TRE of 2.25 mm (histology - ex vivo MRI), 2.22 mm (histology - in vivo mpMRI), and 2.02 mm (ex vivo MRI - in vivo mpMRI). There was no significant difference between TREs of the different pairs of sections or caudal, middle, and cranial tumor parts, respectively. Conclusion: Our initial results show a promising approach to obtaining accurate co-registration between histopathology and in vivo MRI for STS. In a larger cohort of patients, the method established here will enable the prospective identification and validation of in vivo imaging biomarkers for radiation therapy response prediction and monitoring in STS patients via precise molecular and cellular correlation

Year Zero Vol.0 #3

release date: Dec 21, 2022
Year Zero Vol.0 #3
In this action-packed prelude to the hit series, acclaimed horror writer Daniel Kraus (George Romero’s The Living Dead, The Autumnal) unveils four globe-spanning tales from the earliest days of the zombie apocalypse when even the wildest rumors couldn’t measure up to the horror to come. A streetwise Russian cop patrols the back alleys of the opportunistic black market that emerges in response to the crisis…a North Korean soldier observes strange happenings on the DMZ…An E.R. nurse in the rural South fights to protect her hospital from threats without and within…A transgender flight attendant who has observed disturbing clues as she crisscrosses the globe keeps a wary eye on the passenger in seat 23C.

Year Zero Vol.0 #2

release date: Nov 09, 2022
Year Zero Vol.0 #2
In this action-packed prelude to the hit series, acclaimed horror writer Daniel Kraus (George Romero’s The Living Dead, The Autumnal) unveils four globe-spanning tales from the earliest days of the zombie apocalypse when even the wildest rumors couldn’t measure up to the horror to come. A streetwise Russian cop patrols the back alleys of the opportunistic black market that emerges in response to the crisis…a North Korean soldier observes strange happenings on the DMZ…An E.R. nurse in the rural South fights to protect her hospital from threats without and within…A transgender flight attendant who has observed disturbing clues as she crisscrosses the globe keeps a wary eye on the passenger in seat 23C.

Year Zero Vol.0 #1

release date: Oct 12, 2022
Year Zero Vol.0 #1
In this action-packed prelude to the hit series, acclaimed horror writer Daniel Kraus (George Romero’s The Living Dead, The Autumnal) unveils four globe-spanning tales from the earliest days of the zombie apocalypse when even the wildest rumors couldn’t measure up to the horror to come. A streetwise Russian cop patrols the back alleys of the opportunistic black market that emerges in response to the crisis…a North Korean soldier observes strange happenings on the DMZ…An E.R. nurse in the rural South fights to protect her hospital from threats without and within…A transgender flight attendant who has observed disturbing clues as she crisscrosses the globe keeps a wary eye on the passenger in seat 23C.

Deadly Breed

release date: Oct 04, 2022
Deadly Breed
In a future much nearer than you think, where scientific experimentation is exploited for commercial profit, unwisely under-supervised cutting-edge technology creates a menace that threatens the very fabric of human existence. Wrath is the story of a lab rat instilled with human genes whose supersized intelligence helps him to engineer his escape into the world outside the lab: a world vastly ill-equipped to deal with the menace he represents. Modified through advances that have boosted his awareness of humankind''s cruelty in the name of science, and endowed with a rat''s natural proclivity to procreate regularly, Sammy has the potential to sire a rodent army capable of viciously overwhelming the human race.

Zucchero amaro

release date: Jun 29, 2022
Zucchero amaro
Alla fine di Yellow Street c’è una discarica. Al centro della discarica c’è una casa fatiscente. Da lì Robbie ordisce un piano per vendicarsi di tutti i torti subìti nella vita. Arrabbiato, emarginato, abbandonato dai genitori, ha messo insieme un piccolo esercito di tre ragazzini – Jody, Dag e Midge – pronti ad aiutarlo nella crudele impresa: nascondere lamette, veleni e vetri sbriciolati nelle caramelle che quella sera, per Halloween, verranno distribuite ai bambini che busseranno alla sua porta. Gli orologi ticchettano, e sono molti i piccoli innocenti che potrebbero andare incontro a una fine terribile. È Jody a dover procurare le dolci armi di distruzione: porterà a termine il piano malvagio di Robbie o lo farà saltare? Raccontato da voci indimenticabili, il romanzo di Daniel Kraus è al tempo stesso feroce ed emozionante, fa riflettere e fa ridere senza ritegno. Dopo averlo letto non potrete più scartare una caramella con noncurante leggerezza.

La Forme de l'eau

release date: Apr 06, 2022
La Forme de l'eau
Nous sommes en 1963, et Elisa Esposito survit tant bien que mal. Née muette, abandonnée par sa famille, elle travaille de nuit comme femme de ménage au Centre Occam de recherche aérospatiale. Un soir, elle surprend quelque chose qu''elle n''était pas censée voir : un homme amphibie prisonnier d''une cuve, qui doit être étudié par les scientifiques pour faire avancer la course à l''espace de la Guerre Froide. La créature est terrifiante, mais aussi magnifique - elle fascine Elisa. Utilisant la langue des signes, celle-ci établit une communication. Bientôt, la créature devient sa seule raison de vivre. Pendant ce temps, Richard Strickland, le militaire brutal qui a capturé la créature en Amazonie, envisage de la disséquer avant que les Russes ne tentent de s''en emparer. Elisa doit tout risquer pour sauver la créature. Avec l''aide d''une collègue qui souffre du racisme ambiant et d''un voisin malchanceux qui n''a plus rien à perdre, elle met au point un plan d''évasion. Mais Strickland ne l''entend pas de cette oreille. Et les Russes sont bel et bien sur l''affaire... Le fantastique, la romance et l''horreur s''entremêlent dans une histoire d''amour obsédante et tragique/ Le film, réalisé par Guillermo del Toro, a remporté 80 récompenses et a reçu plus de 230 nominations dont : Oscars du cinéma : 4 récompenses dont celles du Meilleur film et Meilleur réalisateur Mostra de Venise : 4 récompenses dont le Lion d''or du meilleur film Golden Globes : 2 récompenses dont celle du Meilleur réalisateur BAFTA Awards : 3 récompenses dont celles du Meilleur réalisateur British Academy Film Awards : 3 récompenses dont celle de la Meilleure réalisation Critics Choice Movie Awards : 4 récompenses dont celles du Meilleur film et du Meilleur réalisateur Directors Guild of America Awards : Meilleure réalisation pour un film « Entre Amélie Poulain et La Belle et la Bête. Avec cette romance, Guillermo del Toro lance un appel à la tolérance, à l''amour de la différence. » Huffington Post (France) « Un évident triomphe artistique, qui réunit les deux facettes du cinéaste : le poète ultra-sensible et l''entertainer universel. » Première « Plus que tout autre chose, cette histoire est une ode à l''idée que la liberté et la grâce peuvent être conquises, mais seulement après avoir brisé les chaînes de la défiance et de la peur. La Forme de l''eau nous entraîne dans un rêve profond. » Time « Ce joyau méticuleusement taillé est l''oeuvre la plus réussie de Guillermo del Toro depuis Le Labyrinthe de Pan. » Hollywood Reporter « Un portrait tout en sensibilité des amours hors des sentiers battus, dont le côté transgressif n''entame ni le réalisme ni la force. » Vanity Fair « Vibrant et enchanteur. » Variety

They Stole Our Hearts

release date: Jan 11, 2022
They Stole Our Hearts
The heart-pounding sequel to They Threw Us Away, about a group of teddy bears looking for a place to call home...and answers to life’s biggest questions. The teddies—clever Buddy, brave Sunny, sweet Sugar, and wise Reginald—have managed to find a child. Life with Darling is far better than any they’ve known. But something''s not right—the promised bliss of Forever Sleep hasn’t come. And they are kept a secret from Darling’s mother, hidden underneath the child’s bed in the dusty darkness. Then the inevitable happens: Mama discovers the teddies. And like all adults they’ve met thus far, she responds with fear and anger. The teddies must watch as one of their friends is destroyed. The remaining trio barely escape, thrust back into a world that does not want them. Disillusioned and lost, the teddies embark on a journey back to the factory where they were created. En route, they find a civilization of discarded teddy bears. The comfort of a town of teddies has its allure...but the need for answers weighs heavy. And there’s something definitely off about these new teddies. Will our heroes accept their strange rules? Or must they dig deep for one more grand adventure to finally learn why they were thrown away?

The Living Dead - Sie kehren zurück

release date: Aug 09, 2021
The Living Dead - Sie kehren zurück
Es beginnt mit einem Toten, der sich plötzlich von der Bahre erhebt und zwei Pathologen angreift. Schnell breitet sich das Phänomen über das ganze Land aus: In einer Wohnwagensiedlung im Mittleren Westen müssen eine junge Schwarze und ein muslimischer Einwanderer gegen ihre toten Freunde kämpfen, die aus ihren Gräbern hervorgekrochen sind. Auf einem Flugzeugträger der US Navy verstecken sich die überlebenden Seeleute vor ihren untoten Kameraden. Ein einsamer Nachrichtensprecher sendet weiter, bis seine wiederauferstandenen Kollegen kommen, um ihn zu zerfleischen. In Washington, D.C., dokumentiert eine autistische Bundesbeamtin die Ausbrüche für eine Nachwelt, die es vielleicht nie geben wird. Im ganzen Land kämpfen die Lebenden gegen die Toten. Wir dachten, wir wüssten, wie diese Geschichte endet. Wir haben uns geirrt.
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