New Releases by Andrew A. Rooney

INTRODUCTION: Paraquat dichloride (commonly referred to as paraquat) is a restricted-use, broad-spectrum herbicide that is commonly used in the United States to control weeds in agricultural and horticultural crops. Because paraquat is not registered for home use, the highest exposures would likely be to those manufacturing and applying paraquat or to those living on or near farms or other areas where paraquat is manufactured or applied. Observational human studies of people who apply pesticides and data from experimental animal studies indicate that long-term, chronic exposure to paraquat might lead to central nervous system toxicity. The National Toxicology Program (NTP) identified paraquat as a potential candidate for systematic review while performing scoping activities to classify environmental exposures associated with Parkinson's disease. Subsequently, NTP became aware that the U.S. Environmental Protection Agency (EPA) Office of Pesticide Programs (OPP) was also evaluating paraquat as part of registration review activities and collaborated with EPA to avoid duplication of effort. OBJECTIVE: The objective of these scoping activities was to identify and characterize peer-reviewed, published scientific literature relevant to paraquat exposure and neurobehavioral and neuropathological endpoints associated with Parkinson's disease in humans and to related models in experimental animals or in vitro studies. METHODS: A scoping review was conducted that followed the NTP Office of Health Assessment and Translation (OHAT) method for systematic review through an abbreviated data extraction step. A comprehensive search strategy was used to retrieve original research records from multiple databases (i.e., Embase, PubMed, Scopus, Web of Science, and TOXLINE) through May\s24, 2018. Relevant records included reports of exposure to paraquat dichloride and neurobehavioral or neuropathological endpoints relevant to Parkinson's disease in humans (such as clinical diagnoses, movement abnormalities, and effects on dopaminergic neurons) in epidemiological studies, experimental animal models of parkinsonism, and in vitro model systems. References were screened in duplicate for relevance and categorized by exposure, outcome, species, and cell type, where appropriate. An interactive evidence map was prepared using Tableau(r) software to enable researchers to explore the health outcome data by key feature (e.g., outcome, study type, animal model). Finally, data extraction of quantitative results was performed using the Health Assessment Workspace Collaborative (HAWC) software for those studies that were the most directly relevant to human Parkinson's disease (e.g., epidemiological studies reporting primary outcomes and studies of mammals exposed to paraquat via exposure routes most representative of human exposures including oral, dermal, and inhalation). RESULTS: The literature search identified 8,685 references, 458 of which were included after screening as relevant to describing the association between exposure to paraquat and the potential development of Parkinson's disease with some reports consisting of multiple lines of evidence and measured endpoints. The human epidemiological evidence consisted of 24 studies with the majority conducted in agricultural workers or people living in or near agricultural areas. A total of 143 experimental animal studies reported measurement of primary health endpoints; 11 were found to have high external validity to human exposure by exposing mammals via a route similar to human exposures (i.e., oral, inhalation, dermal). Supporting mechanistic information was reported in 190 experimental animal studies measuring secondary health endpoints and 244 in vitro studies. DISCUSSION: Using systematic review methodologies, NTP developed a scoping review and evidence maps of published scientific literature to support potential follow-up systematic review and to identify extant research gaps. The evidence maps are interactive, sortable visualizations of quantitative data from epidemiological studies and experimental study characteristics with links to publications. A considerable body of evidence was identified as relevant to paraquat exposure and Parkinson's disease that can be used in developing future systematic reviews as were data gaps and scientific challenges that could be addressed by future research.

This is a curated and comprehensive collection of the most important works covering matters related to national security, diplomacy, defense, war, strategy, and tactics. The collection spans centuries of thought and experience, and includes the latest analysis of international threats, both conventional and asymmetric. It also includes riveting first person accounts of historic battles and wars.Some of the books in this Series are reproductions of historical works preserved by some of the leading libraries in the world. As with any reproduction of a historical artifact, some of these books contain missing or blurred pages, poor pictures, errant marks, etc. We believe these books are essential to this collection and the study of war, and have therefore brought them back into print, despite these imperfections.We hope you enjoy the unmatched breadth and depth of this collection, from the historical to the just-published works.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Who is better prepared to confront challenges and defend principles in a volatile modern world? Those with strong national, religious, ethnic, or tribal identities who accept democracy, or democrats who renounce identity as a kind of divisive prejudice? Natan Sharansky, building on his personal experience as a dissident, argues that valueless cosmopolitanism, even in democracies, is dangerous. Better to have hostile identities framed by democracy than democrats indifferent to identity. In a vigorous, insightful challenge to the left and right alike, Natan Sharansky, as he has proved repeatedly, is at the leading edge of the issues that frame our times.

Offers essays written by the famed commentator that discuss varied topics including media bias, torture, baseball, and holidays.

Best known for his patented curmudgeonly commentary carried weekly on the television news show, 60 Minutes, Rooney here brings his style to the written word. The material doesn't stray very far from the material he developed on television and in his earlier books. Annotation copyrighted by Book News, Inc., Portland, OR

My War is a blunt, funny, idiosyncratic account of Andy Rooney's World War II. As a young, naïve correspondent for The Stars and Stripes, Rooney flew bomber missions, arrived in France during the D-Day invasion, crossed the Rhine with the Allied forces, traveled to Paris for the Liberation, and was one of the first reporters into Buchenwald. Like so many of his generation, Rooney's life was changed forever by the war. He saw life at the extremes of human experience, and wrote about what he observed, making it real to millions of men and women. My War is the story of an inexperienced kid learning the craft of journalism. It is by turns moving, suspenseful, and reflective. And Rooney's unmistakable voice shines through on every page.

A collection of letters by the popular TV commentator to fans, friends, CBS executives, tax collectors, and his children.

KEYWORDS: alligator, testosterone, estradiol, corticosterone, spleen, thymus, season, stress, xenobiotics.

Popular television personality Andy Rooney explores the pleasures and frustrations of everyday life. Presenting the finest of his newspaper essays from the last three years, Rooney offers 126 unconventional pieces on issues affecting us all--from politics, sex, and the economy to ice cream, toilet paper, and dental appointments.

Andy Rooney once again proves why he is one of America’s favorite curmudgeons. Writing at the top of his form, Rooney covers a plethora of subjects, from getting rid of leftovers to the worst job in the world, from travel tips for the travel industry to the best hotel room he ever had. Andy Rooney has an opinion on everything, and in his inimitably irreverent and crotchety style he voices here those things we’ve always wanted to say but never thought we could get away with. You’ll find yourself smiling and frowning and involuntarily bobbing your head in agreement. “As television watchers know, Andrew A. Rooney is a very funny fellow. He can be even funnier in print, as Not That You Asked… aptly demonstrates.”—Associated Press “The greatest thing about Andy is that he makes everyone uncomfortable—especially me.”—Don Hewitt, executive producer, 60 Minutes

This collection includes: A Few Minutes with Andy Rooney, And More by Andy Rooney, and Pieces of My Mind. America's favorite commentator and humorist, explores the joys and frustrations of everyday life. Here are more than 250 essays taken from the best of his television special, 60 Minutes appearances, and nationally syndicated newspaper column.

The fourth collection of his newspaper columns.

Essays taken from the author's syndicated newspaper columns.

Provides a collection of more than fifty of the best of "Sixty Minutes" commentator Andy Rooney's award-winning essays on the current American political, economic, and social scene.

Four great battles of World War 2 - Tarawa, Stalingrad, D-Day and the Battle of the Bulge - in text and photos. Based on TV series "The Twentieth Century."

Personal experiences of the bombing crews of Fortresses and Liberators over Germany.