Most Popular Books by Peter Cameron

Notes on a collection of Hymenoptera from Greymouth, New Zealand, with descriptions of new species is an unchanged, high-quality reprint of the original edition of 1898. Hansebooks is editor of the literature on different topic areas such as research and science, travel and expeditions, cooking and nutrition, medicine, and other genres.As a publisher we focus on the preservation of historical literature.Many works of historical writers and scientists are available today as antiques only. Hansebooks newly publishes these books and contributes to the preservation of literature which has become rare and historical knowledge for the future.

Orig.tit.: ... ISBN 82-588-1059-6 Det er midtsommer og noen venner samles i et hus utenfor New York. Lyle, somer kunstkritiker, kommer på besøk til Marian og John, et ungt velsituert parsom eier et praktfullt sted ved bredden av Hudson-elven. På kort varsel har de fått vite at Lyle har med seg en ny venn, Robert. Det er nøyaktig ett år siden Tony døde av aids i det sammen huset. Tony var nært knyttet til dem alle, han var Lyles elsker og Johns halvbror. Weekenden blir rammen for dramaet som utspiller seg: hver og en har levd ut sorgen over Tony på sin måte. Nå kan de ikke skyve bort sannhetene - week-enden blir et vendepunkt.

The sense of taste allows animals to detect and assess potentially nutritive and toxic substances prior to ingestion. Animals have evolved to detect taste substances that are present in their environment. In fliesDrosophila melanogaster, these include (but may not be limited to), sugars, salts, toxic or noxious bitter compounds, CO2, and water. How do flies detect diverse taste substances? The first part of this thesis describes the results of a microarray-based screen performed in order to identify novel taste detection components. More specifically, a screen comparing RNA from proboscises with and without gustatory neurons enriched for known taste sensillum associated transcripts (gustatory receptors and odorant binding proteins) as well as transcripts with no known gustatory ascribed function. This latter group included transcripts with homology to ion channels and transporters, cytochromes, transcription factors, and proteases. A secondary screen with transgenic flies identified genes whose putative cis-regulatory sequence directed reporter expression in specific subsets of taste neurons, including epithelial sodium channel/degenerin (ENaC/Deg) family members, ionotropic glutamate receptors (iGluRs), an orphan G-protein coupled receptor, and a carbonic anhydrase. The second part of this thesis focuses on the molecular basis for water taste. Here, I identify a member of the ENaC/Deg family, ppk28, as an osmosensitive ion channel that mediates the cellular and behavioral response to water. I use molecular, cellular, calcium imaging and electrophysiological approaches to show that ppk28 is expressed in water-sensing neurons and loss of ppk28 abolishes water sensitivity. Moreover, ectopic expression of ppk28 confers water sensitivity to bitter-sensing gustatory neurons in the fly and sensitivity to hypo-osmotic solutions when expressed in heterologous cells. These studies link an osmosensitive ion channel to water taste detection and drinking behavior, providing the framework for examining the molecular basis for water detection in other animals. The third part of this thesis describes ongoing work with two ENaC/Deg family members termed ppk23 and CG13568. These molecules are largely co-expressed in a subset of taste neurons on the proboscis. Double labeling experiments strongly suggest that these molecules label a novel class of taste neurons. Mutant analysis suggests that these molecules are not involved in salt detection. Here I describe ongoing efforts to identify ligands and chemosensory functions for these two molecules.

In order to examine the effects of exercise intensity on the post exercise elevation in esophageal temperature (DeltaTes), 8 male subjects performed 15 minutes of treadmill running exercise at 3 different exercise intensities, subthreshold (70% VO2max), threshold (84% VO 2max, and suprathreshold (93% VO2max), followed by an upright 45 minute recovery period. In addition, the effects of exercise intensity on the internal temperature threshold for cutaneous vasodilation (Tdil ), as well as post exercise blood pressure, cutaneous blood flow (SkBF) and cardiovascular conductance (DeltaCVC), were examined. Significant differences (p